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LATEST: 2007 impact factor 9.954 from Journal Citation Reports, Thomson 2008
Featured article
Analysis of pairwise cell interactions using an integrated dielectrophoretic-microfluidic system
Using an integrated dielectrophoretic-microfluidic device, we investigated guidance effect of secreted collagen IV and soluble VEGF on endothelial cells at the level of single cell and cell pairs. Cell interaction rules extracted from the experiments of cell pairs were used to mathematically predict branching patterns characteristic of developing multi-cellular blood vessels.
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- Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity
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- Full top 10 list of downloads
Research articles
Analysis of pairwise cell interactions using an integrated dielectrophoretic-microfluidic system
Zhizhong Yin, David Noren, C Joanne Wang, Rob Hang & Andre Levchenko
doi:10.1038/msb.2008.69
Published online: 16 December 2008
Robust and sensitive control of a quorum-sensing circuit by two interlocked feedback loops
Joshua W Williams, Xiaohui Cui, Andre Levchenko & Ann M Stevens
doi:10.1038/msb.2008.70
Published online: 16 December 2008
Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue
Laurence Coquin, Jacob D Feala, Andrew D McCulloch & Giovanni Paternostro
doi:10.1038/msb.2008.71
Published online: 16 December 2008
p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation
Ran Brosh, Reut Shalgi, Atar Liran, Gilad Landan, Katya Korotayev, Giang Huong Nguyen, Espen Enerly, Hilde Johnsen, Yosef Buganim, Hilla Solomon, Ido Goldstein, Shalom Madar, Naomi Goldfinger, Anne-Lise Børresen-Dale, Doron Ginsberg, Curtis C Harris, Yitzhak Pilpel, Moshe Oren & Varda Rotter
doi:10.1038/msb.2008.65
Published online: 25 November 2008
Model-guided design of ligand-regulated RNAi for programmable control of gene expression
Chase L Beisel, Travis S Bayer, Kevin G Hoff & Christina D Smolke
doi:10.1038/msb.2008.62
Published online: 28 October 2008
Finding multiple target optimal intervention in disease-related molecular network
Kun Yang, Hongjun Bai, Qi Ouyang, Luhua Lai & Chao Tang
doi:10.1038/msb.2008.60
Published online: 04 November 2008
Hepatitis C virus infection protein network
B de Chassey, V Navratil, L Tafforeau, M S Hiet, A Aublin-Gex, S Agaugué, G Meiffren, F Pradezynski, B F Faria, T Chantier, M Le Breton, J Pellet, N Davoust, P E Mangeot, A Chaboud, F Penin, Y Jacob, P O Vidalain, M Vidal, P André, C Rabourdin-Combe & V Lotteau
doi:10.1038/msb.2008.66
Published online: 04 November 2008
Reports
The temporal response of the Mycobacterium tuberculosis gene regulatory network during growth arrest
Gábor Balázsi, Allison P Heath, Lanbo Shi & Maria L Gennaro
doi:10.1038/msb.2008.63
Published online: 04 November 2008
News & Views
'Junk' DNA meets the p53 network
Christine Blattner
doi:10.1038/msb.2008.68
Published online: 25 November 2008
Small hairpin RNA as a small molecule sensor
Yaakov Benenson
doi:10.1038/msb.2008.67
Published online: 28 October 2008
Reviews
Selected reaction monitoring for quantitative proteomics: a tutorial
Vinzenz Lange, Paola Picotti, Bruno Domon & Ruedi Aebersold
doi:10.1038/msb.2008.61
Published online: 14 October 2008
Perspectives
High-order combination effects and biological robustness
Joseph Lehár, Andrew Krueger, Grant Zimmermann & Alexis Borisy
doi:10.1038/msb.2008.51
Published online: 05 August 2008
Life Sciences and the web: a new era for collaboration
Jonathan A Sagotsky, Le Zhang, Zhihui Wang, Sean Martin & Thomas S Deisboeck
doi:10.1038/msb.2008.39
Published online: 01 July 2008
More systems biology from NPG & EMBO
A selection of relevant articles hosted by Nature Publishing Group are listed below. More articles can be found on the Systems biology Subject Area page.
